Tag: thiopurine metabolism

Azathioprine and Allopurinol: How to Avoid Toxic Metabolite Buildup in IBD Treatment

Azathioprine and Allopurinol: How to Avoid Toxic Metabolite Buildup in IBD Treatment

LDAA therapy combines low-dose azathioprine with allopurinol to redirect metabolism away from toxic liver-damaging metabolites toward therapeutic compounds. It’s a proven strategy for IBD patients who can’t tolerate standard azathioprine.

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